Nitric oxide ke eng?
Nitric oxide ke khase e hlahisoang ke lisele tse amehang ho ruruha ho amanang le asthma ea allergic kapa eosinophilic.
FeNO ke eng?
Teko ea Fractional exhaled Nitric Oxide (FeNO) ke mokhoa oa ho metha bongata ba nitric oxide ka moea o tsoang.Teko ena e ka thusa ho lemoha lefu la asthma ka ho bontša boemo ba ho ruruha matšoafong.
Tšebeliso ea Clinical ea FeNO
FeNO e ka fana ka tlatsetso e sa tsitsang bakeng sa tlhahlobo ea pele ea asthma le ATS le NICE e e khothalletsang e le karolo ea tataiso ea bona ea hona joale le mekhoa ea ho hlahloba.
| Batho ba baholo | Bana | |
| ATS (2011) | Holimo:> 50 ppb Bohareng: 25-50 ppb Tlase: <25ppb | Holimo: >35ppb Bohareng: 20-35 ppb Tlase: <20 ppb |
| GINA (2021) | ≥ 20 ppb | |
| NICE (2017) | ≥ 40 ppb | >35ppb |
| Tumellano ea Scotland (2019) | > Bakuli ba 40 ppb ICS-ba sa tsebeng letho > bakuli ba 25 ppb ba nkang ICS |
Likhutšoaane: ATS, Mokhatlo oa Amerika oa Thoracic;FeNO, karoloana ex- haled nitric oxide;GINA, Global Initiative bakeng sa Asthma;ICS, ho hema corticosteroid;NICE, Setsi sa Naha sa Bophelo bo Botle le Tlhokomelo e Ntle.
Litaelo tsa ATS li hlalosa maemo a phahameng, a mahareng, le a tlaase a FeNO ho batho ba baholo e le> 50 ppb, 25 ho 50 ppb, le <25 ppb, ka ho latellana.Ha ba ntse ba le bana, maemo a phahameng, a mahareng, le a tlaase a FeNO a hlalosoa e le> 35 ppb, 20 ho 35 ppb, le <20 ppb (Letlapa la 1).ATS e khothalletsa tšebeliso ea FeNO ho tšehetsa tlhahlobo ea asthma moo ho hlokahalang bopaki ba sepheo, haholo-holo ha ho fumanoa hore ho na le ho ruruha ha eosinophilic.ATS e hlalosa hore maemo a phahameng a FeNO (> 50 ppb ho batho ba baholo le> 35 ppb ho bana), ha a hlalosoa litabeng tsa bongaka, a bontša hore ho ruruha ha eosinophilic ho teng ka karabelo ea corticosteroid ho bakuli ba nang le matšoao, ha maemo a tlaase (<25 ppb ho batho ba baholo). le <20 ppb ho bana) li etsa hore maemo ana a sa lebelloang le a mahareng a tlameha ho hlalosoa ka hloko.
Litaelo tsa morao-rao tsa NICE, tse sebelisang maemo a fokolang a FeNO ho feta ATS (Letlapa la 1), li khothalletsa tšebeliso ea FeNO e le karolo ea mosebetsi oa ho hlahloba moo ho hlahlojoang ha asthma ho nkoang ho batho ba baholo kapa moo ho nang le ho se tsitse ha bana.Maemo a FeNO a boetse a hlalosoa maemong a kliniki le liteko tse ling, joalo ka tlhahlobo ea bronchial provocation e ka thusa tlhahlobo ka ho bonts'a khatello ea maikutlo ea moea.Tataiso ea GINA e amohela karolo ea FeNO ho khethollang ho ruruha ha eosinophilic ho asthma empa ha joale ha e bone karolo ea FeNO ho li-algorithms tsa tlhahlobo ea asthma.Tumellano ea Scotland e hlalosa li-cut-offs ho ea ka ho pepeseha ha steroid ka litekanyetso tse ntle tsa > 40 ppb ho bakuli ba steroid-naive le > 25 ppb bakeng sa bakuli ba ICS.
Nako ea poso: Mar-31-2022